Sleeping well doesn’t just depend on “going to bed early”; sleep quality and continuity are essential for rest, energy recovery, and maintaining mental and physical health. Many people experience insomnia, difficulty falling asleep, or frequent awakenings, which can negatively affect daily performance.
In this context, Centenarian Road’s SLEEP supplement, combining Melotime® (extended-release melatonin) with chamomile apigenin, stands out as a natural, science-backed solution to improve both sleep onset and maintenance.
Benefits of Melatonin and Apigenin
Helps You Fall Asleep Faster
Melatonin is the key hormone regulating sleep. Its supplementation, especially in extended-release formulations like Melotime®, accelerates sleep onset and supports continuous rest. A meta-analysis of 19 clinical trials published in PubMed confirmed that melatonin reduces sleep latency and increases total sleep time, with effects that remain consistent over long-term use.
Deep and Restorative Sleep
SLEEP promotes deeper, more restorative sleep, allowing the body and mind to recover efficiently. This is particularly beneficial for those who wake frequently or have difficulty maintaining sleep.
Natural Relaxation with Apigenin
Apigenin, extracted from chamomile (Matricaria chamomilla), enhances relaxation and reduces pre-sleep anxiety, helping create a sense of calm and supporting uninterrupted sleep without side effects.
How SLEEP Works
The supplement combines two complementary mechanisms:
- Extended-release melatonin (Melotime®): mimics the body’s natural secretion pattern, releasing part immediately to help you fall asleep and the rest gradually to maintain sleep throughout the night.
- Chamomile apigenin: activates GABA receptors in the brain, promoting relaxation and reducing mental tension.
This combination delivers a comprehensive effect on sleep, addressing both sleep initiation and continuity.
Dosage and How to Take It
For optimal results:
- Take 30–60 minutes before bedtime.
- Can be taken with or without food.
- The 1.9 mg extended-release melatonin is designed to be effective without causing dependency or morning grogginess.
Scientific Evidence
A PubMed meta-analysis (Ferracioli-Oda E et al., 2013) confirms that exogenous melatonin is effective at reducing sleep latency and improving sleep duration and quality, without losing efficacy over continued use—unlike many pharmaceutical hypnotics.
Who Is SLEEP For?
- People with insomnia or difficulty falling asleep
- Night shift workers or those with irregular schedules
- Frequent travelers (jet lag)
- Menopausal women needing fewer night awakenings and better sleep
- Athletes seeking improved muscle recovery and performance
- Individuals with mild stress or anxiety affecting sleep
Frequently Asked Questions About Melatonin and Apigenin
What is melatonin for?
Melatonin is a natural hormone that regulates the sleep-wake cycle. Supplementing with melatonin helps you fall asleep faster, improve sleep duration and quality, and maintain a balanced circadian rhythm. It is especially useful for insomnia, jet lag, night shift work, or sleep disruptions caused by stress.
Which foods contain melatonin?
Several foods naturally contain melatonin, although in smaller amounts than supplements:
- Tart cherries
- Bananas and grapes
- Tomatoes and nuts
- Oats and corn
Including these foods in your diet may help support natural sleep, but for more severe sleep difficulties, a high-quality melatonin supplement is recommended.
What is the best melatonin?
The best melatonin supplement is one that:
- Has an extended-release formulation (like Melotime®) to help you fall asleep and stay asleep through the night.
- Is of high purity and pharmaceutical-grade quality, without unnecessary additives.
- Provides an effective dose without dependency, typically between 1–3 mg.
Centenarian Road’s SLEEP supplement meets these standards, supported by scientific evidence demonstrating its efficacy.
What is apigenin?
Apigenin is a natural flavonoid found in chamomile (Matricaria chamomilla) that helps promote relaxation and reduce anxiety. It is included in sleep supplements to enhance sleep quality, allowing for continuous, deep rest without morning grogginess.


