1 5

Stress

Stress

Ashwagandha KSM-66® extract with 5% withanolides together with Holy Basil extract – Holixer®.

Informed Sport Informed Sport (Doping Free)
Lab Guaranteed Composition Lab Guaranteed Composition
Main Pollutants Free Main Pollutants Free
Gluten Free Gluten Free
Good Manufacturing Practices Good Manufacturing Practices
Not Genetically Modified Not Genetically Modified
€34,95 EUR
€34,95 EUR
Sale Sold out
Taxes included.
View full details
 
 

WHAT ARE ASHWAGANDHA AND HOLY BASIL?

Stress is ubiquitous and its prevalence is increasing worldwide. It is a major risk factor in the development of physical and psychiatric conditions. It negatively affects cognitive ability, memory, sleep quality, executive functions, and the overall psychological well-being of individuals. All of these factors contribute to the development of somatic problems (1)1. Jianhui W et al. Stress and cognition. Frontiers in Psychology . 2017;8:p. 970..

Ashwagandha, or withania somnifera dunal, commonly known as Indian ginseng or winter cherry, has traditionally been used as an adaptogen.

Adaptogens are herbal extracts that increase an organism’s ability to adapt to environmental stressors and decrease the damage caused by those stressors (2)2. Kulkarni SK et al. Withania somnifera: an indian ginseng. Prog Neuropsychopharmacol Biol Psychiatry. 2008;32:1093–105..

The main chemical constituents of pharmacological importance in the ashwagandha plant are the withanolides.

Holy basil, or tulsi, is an aromatic plant native to Southeast Asia with adaptogenic properties. Its beneficial effects derive from its numerous bioactive components, such as eugenol, carvacrol, ursolic acid, β-caryophyllene and rosmarinic acid (3)3. Thakur S et al. Tulsi – a review based upon its ayurvedic and modern therapeutic uses. Int J Inf Res Rev. (2021) 8:263–72. 10.52403/ijrr.20210534.

 
 

WHY THIS FORMAT?

A dosage of 600mg per day of the dry extract of Ashwagandha KSM-66® with 5% withanolides has been shown to reduce cortisol, thus improving symptoms associated with stress and anxiety (4)4. Salve J et al. Adaptogenic and anxiolytic effects of Ashwagandha root extract in healthy adults: a double-blind, randomized, placebo-controlled clinical study. Cureus. 2019;11:e6466..

Similarly, supplementation with holy basil extract – Holixer® at doses greater than 125mg/day has proven to reduce objective and subjective stress markers (5)5. Lopresti AL et al. A randomized, double-blind, placebo-controlled trial investigating the effects of an Ocimum tenuiflorum (Holy Basil) extract (HolixerTM) on stress, mood, and sleep in adults experiencing stress. Front Nutr. 2022 Sep 2;9:965130..

 
 

BENEFITS OF ASHWAGANDHA AND HOLY BASIL

To date, scientific research has proven that Ashwagandha extract supplementation (6)6. Majeed M et al. A standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults by modulating stress hormones: Results from a randomized, double-blind, placebo-controlled study. Medicine (Baltimore). 2023 Oct 13;102(41):e35521. reduces cortisol levels and increases serotonin production, thus reducing stress and anxiety levels.

Holy basil extract has also proven to improve these stress markers (5)5. Lopresti AL et al. A randomized, double-blind, placebo-controlled trial investigating the effects of an Ocimum tenuiflorum (Holy Basil) extract (HolixerTM) on stress, mood, and sleep in adults experiencing stress. Front Nutr. 2022 Sep 2;9:965130..

Other benefits associated with these adaptogens include improved sleep quality, cognitive performance, and mood.

 

BIBLIOGRAPHIC REFERENCES

1. Jianhui W et al. Stress and cognition. Frontiers in Psychology . 2017;8:p. 970.

2. Kulkarni SK et al. Withania somnifera: an indian ginseng. Prog Neuropsychopharmacol Biol Psychiatry. 2008;32:1093–105.

3. Thakur S et al. Tulsi – a review based upon its ayurvedic and modern therapeutic uses. Int J Inf Res Rev. (2021) 8:263–72. 10.52403/ijrr.20210534

4. Salve J et al. Adaptogenic and anxiolytic effects of Ashwagandha root extract in healthy adults: a double-blind, randomized, placebo-controlled clinical study. Cureus. 2019;11:e6466.

5. Lopresti AL et al. A randomized, double-blind, placebo-controlled trial investigating the effects of an Ocimum tenuiflorum (Holy Basil) extract (HolixerTM) on stress, mood, and sleep in adults experiencing stress. Front Nutr. 2022 Sep 2;9:965130.

6. Majeed M et al. A standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults by modulating stress hormones: Results from a randomized, double-blind, placebo-controlled study. Medicine (Baltimore). 2023 Oct 13;102(41):e35521.